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First Released in 1986 by the University of Delaware, GUIDO (Graded Units for Interactive Dictation Operations) was self-paced Ear Training instructional software designed by and for use at the University of Delaware. It was originally programmed on a Burroughs 6700 and later ported to the PLATO system, before it was redesigned for use on the IBM-PC/XT/AT.
Monologue is a speech synthesis program that reads text from the screen. Versions exist for both DOS and Windows.
MusicPrinter Plus, from Temporal Acuity Products, Inc, is a musical notation program for MS-DOS. It supports CGA, EGA, and VGA video as well as MIDI playback.
Roland EASE is a MIDI music editor and playback program designed specifically for the Roland MT32. It supports a variety of effects, and editing features.