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AUTOMAP is a computerized US roadmap from NextBase that shows major US roads. It can plot travel routs, and displays various regional information.
Microsoft MapPoint is a business oriented mapping program. It includes geographic and demographic data across the US and enables integration with external databases or programs. It was targeted towards businesses as a lower cost solution than a full blown Geographic Information System (GIS).
SoftKey Key Master Maps is a road map of the entire USA on a CD.