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AutoCAD, from Autodesk and first released in 1982, is a powerful Computer Aided Design tool. It was, and still is, often considered the standard for CAD tools. Primarily for the IBM PC platform, it was ported to x86 machines with higher video resolutions such as the Zenith Z-100 and NEC APC. Intermittently, versions for the Macintosh appeared. Later versions use a dongle copy protection.
ColorWorks is a powerful, full-featured, photo editing program designed exclusively for OS/2. It is a native 32-bit OS/2 application and makes use of OS/2 multitasking, multithreading, and SMP capabilities. It has many features and tools that make it comparable to most other image editors.
Footprint Works is an office suite for OS/2 that includes a word processor, spreadsheet, and database. Later versions were known as IBM Works and were bundled with OS/2 Bonus Packs.
GrafTalk is a business graphics package for CP/M systems. It can generate pie charts, line plots, symbol plots, composite plots, text, and color. It was considered "easy" to use, with menus, but also features a powerful command line interface.