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TI-Artist, from INSCEBOT INC., is an easy to use general purpose drawing package for the TI-99/4A (not the original /4) that makes use of the high resolution bit-mapped graphics mode.
Unify is a relational database for Unix based systems. There was also a DOS version.
VideoWorks is a Macintosh animation program that eventually became Macromedia/Adobe Director.
Xerox Globalview is a desktop environment and office suite originally developed for the Xerox Star. It was developed in the MESA programming language on the Xerox Star, and ported to Sun Solaris, OS/2, and Windows 3.1 (The OS/2 version requires a MESA emulator card).